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ESM
Current strategies to combat the extraluminal route of infection are focused on Exit Site Management, or ESM.
Current strategies to combat the extraluminal route of infection are focused on Exit Site Management, or ESM.
NexSitetm Technology
Marvao’s patent pending NexSitetm technology aims to reduce the rate of CRBSIs by managing the exit sites of Central Venous Catheters by promoting the formation of a biological seal around the catheter. This natural seal is intended to block the route for bacteria through the catheter exit site.
The NexSitetm technology consists of two pieces – a transcutaneous dacron cuff mounted on a catheter (Fig1) and a subcutaneous port with a dacron skirt. (Fig2)
The transcutaneous catheter cuff is positioned in the subcutaneous port with the Dacron surfaces aligned to create a three-dimensional tissue ingrowth scaffold. (Fig3)
The catheter cuff and port skirt provide a 3-dimensional scaffold to facilitate tissue ingrowth. After placement, blood and tissue infiltrate the cuff and skirt promoting the formation of a natural barrier between the internal and external environments. (Fig4)
As the wound healing process progresses, tissue grows into the catheter cuff and port skirt, potentially reducing the risk of infection via the extraluminal route. (Fig5)